This dual system, Serum and Accelerator, is provided in 5 ml bottles. The full-size 30ml duo can be purchased from here
The AnteAGE® Skincare System (Serum and Accelerator duo) is clinically proven to restore healthy skin and reverse ageing in five-weeks.
With daily use, this System improves the health and appearance of skin at any age.
The stem cell technology behind AnteAGE® MD is cutting edge and published in multiple peer-reviewed medical journals.
The two products address all the problems associates with unhealthy skin, including redness and breakouts.
The scientists involved with developing the products have made it possible to harness in skincare, the healing bio-signals that are omitted naturally. These Growth Factors and Cytokines form part of the complex language, that is part of the response to healing from injury and environmental exposure.
The serums quickly absorb into your skin with a high concentration of physiologically balanced Stem Cytokines™ (derived from human bone marrow stem cells) fortified with two recombinant Growth Factors, TGF-β3 and IGF-1. A nanoliposomes delivery system ensures proper penetration.
AnteAGE® MD System contains twice the Stem Cytokines found in AnteAGE (green/blue packaging), along with twenty-oneadditional ingredients with proven anti-ageing, pro-healing and anti-inflammatory benefits. Each with peer-reviewed and published scientific proof of value in producing healthier younger-looking skin.
The corrective properties achieved from using AnteAge are very unique. It benefits every aspect of the skin, from how it functions on a cellular level to its appearance.
Products containing conditioned media from bone marrow stem cell cultures demonstrate a potent anti-inflammatory effect.
AnteAGE® is suitable for all skin problems and types.
Growth Factors & Cytokines
Palmitoyl Oligopeptide & Palmitoyl Tetrapeptide-7
Catechins & Flavonoids
Ceramides & Phospholipids
Growth Factors & Cytokines
Bakuchiol (derived from bakuchiol seed) has been compared to Retinol (a Vitamin A derivative) for improving wrinkles and ageing skin.
Human Beta-Defensin 3
Tetrahexyldecyl Ascorbate (Vitamin C)
Tocopheryl Acetate (Vitamin E)
Panthenol (Vitamin B5)
Grape Seed Extract
The AnteAGE® Skincare System was in development for 3+ years and launched in 2012 by The Cellese Corporation, the research laboratory and manufacturing is done in California, USA.
The key difference between growth factors (GF's) made by other brands is that the growth factors are harvested from bone marrow-derived mesenchymal stem cells (MSC's) a cytokine, "powerhouses" and not fibroblasts (fetal foreskin derived) or fat cells (adipocytes) extracted through liposuction.
MSC stem cells produce fifty times the concentration of key GF’s compared to fibroblasts.
Within the body, MSCs deplete as you get older. In fact, at age fifteen, one out of every 10,000 of the cells in your bone marrow are MSCs. At age fifty, only 2.5% of these cells remain.
This makes sense when you realise the different roles these cell types play in wound healing and regeneration. Fibroblasts are really the corporals in that war, taking orders from the generals – the stem cells. Stem cells bark the orders, fibroblasts listen and do the grunt work.
Extracted from an article written by founder Dr. George Taylor;
"MSC’s are grown in “farms” of millions of MSC’s under strict sterile conditions in a university laboratory. Their environment is highly controlled. We mimic the niche they live in with the body. We “talk” to them. They produce abundant cytokines in regenerative patterns. We isolate them, leaving all that cell stuff behind. Cytokines are further processed to package them for delivery through the skin (nanoliposomes)." www.barefacedtruth.com
"The human stem cell-derived growth factors are completely natural to humans. Organic if you will, in that they are a perfect molecular match to the same growth factors our own bodies make. That means that allergic reactions to these molecules are pretty much nonexistent." Extracted from blog article www.barefacedtruth.com
The first step in the AnteAGE® Skin Care System is a water-soluble blend of actives in a Serum. That flood the skin with the most anti-inflammatory and regenerative ingredients to prime it's the ability to repair, regenerate, and produce quality, Type One collagen. The characteristics of this tissue, create beautifully
The second step in the AnteAGE® Skin Care System is the Accelerator– a lipid-soluble form of active ingredients that acts as a compliment and a synergistic topical to our serum. The Accelerator helps to provide a well-rounded approach to skin health and it contains a high dose of lipid-soluble antioxidants housed in a base of ceramides and phospholipids.
If you wrap your molecules in a lipid envelope it can sneak into the spaces between cells which is lipid-soluble because it helps to make the substance electrically neutral.
They form a two-layer structure, called the lipid bilayer, with the polar head facing out on each surface to interact with water, and with the neutral “tails” driven inward and pointing toward one another. The lipid bilayer is the structural basis of all cell membranes and is nearly impermeable to ions and most polar molecules. Proteins embedded in the phospholipid matrix transport many substances through the membrane.
Definition of terms:
1. Bio-signals refers to cytokines & growth factors produced through laboratory culture of human cells.
2. Conditioned media is the name given to the nutrient culture broth after all cells have been filtered out and discarded. It contains the biosignals produced by the cells during culture.
3. Lysed cells are cells that have been ruptured or burst using repeated freeze-thaw cycles.
4. Exosomes are a type of extracellular vesicle that contain constituents (protein, DNA, and RNA) of the cells that secrete them. They are taken up by distant cells, where they can affect cell function and behaviour.
The research was conducted by Founders, Dr. John Sanderson and Dr. George Taylor. They are also the authors of an educational website called barefacedtruth.com that gives a very detailed explanation of the scientific discover around GF and is also a platform for debating their use in skincare.
AnteAGE® by Cellese Recent research revealed the important role bone marrow stem cells play in tissue repair and healing throughout the body, particularly in the skin.
The founders choose to employ not fibroblasts, but stem cells, and indeed a particular class of stem cell that is the subject of intensive work in many other stem cell laboratories around the world.
Like red cells, white cells, and platelets, which also originate in the bone marrow, these stem cells enter the bloodstream where they are carried to all tissues. Upon arrival at injuries, some may differentiate into cell types needed for repair (e.g. muscle, cartilage, nerve, etc.). Their major role, however, is to act as command and control of other nearby cells involved in healing. The pattern of bio-signals in conditioned media derived from the culture of bone marrow stem cells is strongly anti-inflammatory. On the basis of healing physiology, and the known deleterious effects of inflammation on the skin, bone marrow-derived mesenchymal stem cells appear to be the preferred cell to culture to obtain bio-signals for use in products to be applied to the skin. Clinical evidence supports this conclusion. Bone marrow stem cells are typically obtained from young adults in their early 20’s.
Claims: AnteAGE was effective in improving twelve parameters of skin health and appearance in 45 women and 4 men aged 30 to 75. These twelve parameters were: Tone, Dryness, Brightness, Softeners, Pore Size, Blotchiness, Redness, Age Spots, Fine Lines, Texture, Colour Blend, Deep Lines.
Clinical Results: 85% saw improvement in 6 or more criteria; 61% saw improvement in 9 or more criteria; 32% saw improvement in all 12 criteria. There were forty-eight participants and the study lasted five-weeks.
Dispense 1-2 pump and apply to clean skin, both morning and evening. Start the application on the forehead and spread down the face using fingertips. Tap any residue around the eye bone and lip. Suitable to use on the neck form the onset.
The stem cells are sourced only from the bone marrow of young, healthy, pre-screened adult donors. Stem cell cytokines also contain none of the original cell parts themselves, only the beneficial growth factors they produce.
The healing chemical signals produced by the mesenchymal stem cells (growth factors and cytokines) are harvested. The products are 100% free of inflammatory cells, cell fragments, RNA, or DNA.
The Serum contains only the harvested growth factors and cytokines.
The formulation is very stable and does not require refrigeration
The point after opening is recommended at twelve months